呪 means “curse, spell”

のろう · norou

Also: charm, malediction

Kun'yomi (Japanese reading)
まじなう, のろい, まじない, のろう
On'yomi (Chinese reading)
ジュ, シュ, シュウ, ズ

JLPT N1 · Taught in secondary school · 8 strokes

The story

A mouth (口) beside 兄, a figure that is nearly all mouth: words spoken to call down harm. 呪う is to curse, a 呪文 is a spell, and 呪術, sorcery, named the hit manga 呪術廻戦, Jujutsu Kaisen. The same 兄 prays in 祝, to celebrate.

Used in 呪う (norou, to curse), 呪い (noroi, curse), and 呪文 (jumon, spell/incantation)

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Readings from KANJIDIC2, © EDRDG, CC BY-SA.